Samuel Fuller (1580 - 1633) was a passenger on the 1620 voyage of the Pilgrim ship Mayflower and singed the Mayflower Compact. He became a respected church deacon and the physician for Plymouth Colony.
Fuller was a son of Robert Fuller, a butcher. He was baptized on January 20, 1580 at Redenhall, co. Norfolk, England. He was a member of the Separatist religion which was not allowed in England.